The term hepatosplenomegaly is a mouthful, but it simply refers to the spleen and liver enlargement of the human body. It occurs in severe diseases, and as a consequence, a detailed diagnosis is needed. So, how do you know that these parts are bigger? Enlargement of the liver has been noted on palpation. A little lower than the right rib arch, there is a bulge of that organ.
This can, in turn, put pressure on other organs within the liver itself, leading to painful symptoms. The spleen, on the other hand, is harder to palpate. However, a patient may find it difficult to bend and feel discomfort while doing some activities. If such symptoms are seen in you, it might be a sign of sarcoidosis, which also causes liver dysfunction.