The disease process involves the skin or mucous membranes. Most lupus patients observe some skin manifestations at a certain stage of the disease. Skin symptoms are highly variable and diverse. It is possible to experience symptoms associated with scarring and atrophy. Other presentations include patients developing skin blistering and skin lesions secondary to vasculitis. The presence of skin rashes in several parts of the body is a typical symptom related to lupus.
It can present as a macular or papular rash. It can also appear as rosacea, seborrhoeic dermatitis, or psoriatic lesions. The rash would develop on the face, neck, or other parts of the body. It may present with scarring or non-scarring alopecia from time to time. This explains why the disease tends to need aggressive treatment to reduce scarring and dyspigmentation.